How Can Fixing a Few Cells Treat the Whole Body? — DECODE No. 3

At: Jul 13  |  Categories: Cell & Gene Therapy
  • DECODE
  • cross-correction
  • gene therapy
  • cell therapy
  • Fabry disease
  • mechanism of action
  • rare disease

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(Last time: lyso-Gb3, the biomarker that tracks Fabry disease.)

 

Here's a beautiful shortcut in biology: to treat the whole body, you don't have to fix every cell. Fix some, and they secrete a helper the neighboring cells absorb and put to work — spreading the benefit outward.

 

There's a two-word name for this generous phenomenon. What is it? Drop your guess in the comments below.

 

Follow the whole series: https://bit.ly/Glafabra-TTW

 

@Brian Christie @Neva West @Chris Hopkins @Tetsu Yung

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