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(Answer to the question last time on August 27: roughly 40 percent of ERT patients develop anti-drug antibodies over time, which can reduce how well the infused enzyme works.)

It's often the very first symptom Fabry patients notice, frequently in childhood — a burning, tingling pain in a specific part of the body.

Where in the body does this early, telltale Fabry pain usually show up? Drop your guess in the comments below.

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@Brian Christie  @Neva West @Chris Hopkins @Tetsu Yung 

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